Hormones play a key role in keeping the reproductive system functioning properly. One of the most important hormones in this process is Follicle Stimulating Hormone (FSH). It helps the ovaries produce eggs and regulate the menstrual cycle. However, in individuals with Endometriosis, this delicate hormonal balance can be thrown off, affecting fertility, ovulation, and even worsening symptoms of the condition.
What is FSH?
Follicle-stimulating hormone (FSH) is a key reproductive hormone that signals the ovaries to mature eggs for ovulation. It plays a crucial role in regulating the menstrual cycle and fertility.
The Problem in Endometriosis
In individuals with Endometriosis, the ovaries may not respond properly to FSH stimulation. This can lead to hormonal imbalances that increase estrogen production, fueling the progression of Endometriosis.
The Hormonal Imbalance Cycle
Higher FSH Levels → Increased Estrogen Production
- When the ovaries fail to respond adequately to FSH, the body compensates by producing more FSH to stimulate egg development.
- This excessive FSH triggers higher estrogen levels, which encourages the growth of Endometriosis Material-like tissue outside the uterus.
More Estrogen → Worsening of Endometriosis
- Estrogen is the primary hormone driving Endometriosis. The more estrogen available, the more these lesions grow, bleed, and cause inflammation.
- This sets up a vicious cycle where Endometriosis continues to progress, despite the body’s attempts to regulate hormones.
Irregular Menstrual Cycles
Endometriosis-related hormonal imbalances disrupt ovulation, leading to:
- Irregular or absent ovulation (anovulation), making conception difficult.
- Shortened or prolonged luteal phases, affecting the implantation of a fertilized egg.